For Eastern whitetail, any action chambered in any caliber from .243 to 30-06 is perfect. I've personally shot deer with semi-autos, lever actions, and bolt actions in .260 Rem, 6.5 x 55 Swed, .270 Win, 7mm-08 Rem, .308 Win, 30-30 Win, 30-06 Sprg, and .32 Win Special; all of those deer ended up...